Fortune: “Picture this: You’ve spent weeks polishing your resume, navigating multiple rounds of interviews, and finally, you land a 45-minute dinner with the boss. You think you’ve won him over. Then he asks, “Do you have any questions for me?” If your answer is a blank stare or “Nope, I’m fine,” consider yourself on thin ice. “The number one red flag for me is when someone doesn’t ask questions towards the end of an interview,” Twilio CEO Khozema Shipchandler exclusively tells Fortune…Even if you have lots of questions up your sleeve, there’s one word he’s listening out for throughout the interview that could cost you the job: Using “I” a lot in conversation.”
The Generalist on the Jensen Huang Playbook: “Understand the “essence” of your industry. “Torture” employees into greatness. Pick “zero-billion-dollar” markets. Ignore your customers. Ship the whole cow. Move at the “speed of light”. The best plan is no plan. Minimize information mutilation.”
Vasant Dhar: “In tennis, we can think of edge as deriving from some combination of a player’s capabilities. These would be things like speed, power, agility, anticipation, fitness, versatility, guile and mental toughness. Guile requires other foundational capabilities such as speed and agility. The edge manifests itself in the quality of shots relative to the opponent’s, which shows up at the point level. But an edge is very hard to achieve in highly competitive situations. Everyone is using the best equipment, hiring extremely talented coaches and management, and practicing with extreme intensity for hours on end. Achieving a 50% winning record isn’t easy. It requires the most up to date infrastructure to stay even in the game. Without investment, edge erodes. It’s the same in investing. Doing better than 50% is hard. Improving the edge by a mere percentage point above even is excruciatingly difficult, but the spoils are well worthwhile.”
WSJ: “Sequencing a genome two decades ago cost more than a Beverly Hills mansion, and how much demand could there be to diagnose diseases that by definition are rare? Turns out, a lot. As sequencing costs have plunged, GeneDx has the potential to revolutionize the field of rare diseases—which, collectively, are more common than most people realize. The Food and Drug Administration estimates that some 30 million Americans suffer from rare diseases. Many are never diagnosed, and GeneDx aims to change that. It sequences DNA for mutations that are responsible for thousands of disorders. A single deletion or duplication in the genetic code can result in misshapen or missing proteins that are vital to a variety of physiological processes. A case in point: Duchenne muscular dystrophy can result from a mutation or deletion in any of the 79 protein-encoding genes that together produce the dystrophin protein, which stabilizes muscles.”
Business Standard on Flipkart: “In FY25, advertising revenue rose 27 per cent to ₹6,317 crore from ₹4,973 crore a year earlier.”
